Associations between psychological factors and health-related quality of life and global quality of life in patients with ALS: a systematic review
Language: 
English
Short Title: 
Associations between psychological factors and health-related quality of life and global quality of life in patients with ALS
Abstract: 

OBJECTIVE: To systematically identify and appraise evidence on associations between psychological factors (moods, beliefs, personality) and Health-related QoL (HRQoL) and/or global QoL in patients with Amyotrophic Lateral Sclerosis (ALS). METHODS: A systematic review was conducted in several online databases (PsycINFO, EMBASE, PubMed and CINAHL) up to October 2015. Articles were included if they reported associations between psychological factors (moods, beliefs and personality) and HRQoL and/or global QoL in an ALS population. The search was limited to empirical studies, published in English, which provided quantitative data. The methodological quality of the included articles was assessed. RESULTS: In total, 22 studies were included. Mood was investigated in 14 studies, beliefs in 11 studies and personality in one study. Fifteen different psychological factors were extracted and assessed using 24 different measures. Twelve different QoL measures were used in the selected studies, subdivided into seven different HRQoL measures and five different global QoL measures. Higher levels of anxiety and depression appeared to be related to a poorer HRQoL, whereas a higher level of religiosity seemed to be associated with better global QoL. No conclusive associations were found for confusion-bewilderment (mood), spirituality, mindfulness, coping styles, hopelessness, perception of burden, cognitive appraisal (beliefs), neuroticism, extraversion, openness, agreeableness and conscientiousness (personality), due to insufficient or inconsistent evidence. Religiosity and spirituality appeared to become more positively associated over time. CONCLUSIONS: Our results suggest that higher levels of anxiety and depression are related to a poorer HRQoL, whereas higher levels of religiosity appeared to be related to better global QoL. Associations might change during the disease course. This review supports the importance of psychological factors with regard to ALS care. Further research is needed to supplement the available evidence and to investigate how psychological factors can be modified to improve QoL. REVIEW REGISTRATION NUMBER: PROSPERO 2015:CRD42015027303.

Author(s): 
van Groenestijn, Annerieke C.
Kruitwagen-van Reenen, Esther T.
Visser-Meily, Johanna M. A.
van den Berg, Leonard H.
Schröder, Carin D.
Item Type: 
Journal Article
Publication Title: 
Health and Quality of Life Outcomes
Journal Abbreviation: 
Health Qual Life Outcomes
Publication Date: 
7/20/2016
Publication Year: 
2016
Pages: 
107
Volume: 
14
Issue: 
1
ISSN: 
1477-7525
DOI: 
10.1186/s12955-016-0507-6
Library Catalog: 
PubMed
Extra: 
PMID: 27439463 PMCID: PMC4955215

Turabian/Chicago Citation

Annerieke C. van Groenestijn, Esther T. Kruitwagen-van Reenen, Johanna M. A. Visser-Meily, Leonard H. van den Berg and Carin D. Schröder. 7/20/2016. "Associations between psychological factors and health-related quality of life and global quality of life in patients with ALS: a systematic review." Health and Quality of Life Outcomes 14: 1: 107. 10.1186/s12955-016-0507-6.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1186/s12955-016-0507-6 | issn = 1477-7525 | volume = 14 | pages = 107 | last = van Groenestijn | first = Annerieke C. | coauthors = Kruitwagen-van Reenen, Esther T., Visser-Meily, Johanna M. A., van den Berg, Leonard H., Schröder, Carin D. | title = Associations between psychological factors and health-related quality of life and global quality of life in patients with ALS: a systematic review | journal = Health and Quality of Life Outcomes | date = 7/20/2016 | pmid = | pmc = }} </ref>