Live fast, die young: new lessons in mammalian longevity
Language: 
English
Short Title: 
Live fast, die young
Abstract: 

Can we extend human lifespan? Do we need to regulate lifestyle choices or can we simply pop a pill to make us live longer? These are questions raised by two new studies demonstrating significant lifespan extension in mice fed the drug rapamycin in their diet and in calorically restricted rhesus monkeys. The excitement generated by these papers is a consequence of their novelty and possible applicability to humans: the mouse study on rapamycin is the first to highlight a drug that given in the diet late in life leads to increased mammalian longevity, and the Wisconsin monkey study is the first to report significant lifespan extension and delay in age-associated morbidity in nonhuman primates following adult-onset caloric restriction. These papers are discussed here in the context of current knowledge of molecular mechanisms of aging.

Author(s): 
Cox, Lynne S.
Item Type: 
Journal Article
Publication Title: 
Rejuvenation Research
Journal Abbreviation: 
Rejuvenation Res
Publication Date: 
2009-08
Publication Year: 
2009
Pages: 
283-288
Volume: 
12
Issue: 
4
ISSN: 
1557-8577
DOI: 
10.1089/rej.2009.0894
Library Catalog: 
NCBI Published Medical (?)
Extra: 
PMID: 19725776

Turabian/Chicago Citation

Lynne S. Cox. 2009-08. "Live fast, die young: new lessons in mammalian longevity." Rejuvenation Research 12: 4: 283-288. 10.1089/rej.2009.0894.

Wikipedia Citation

<ref> {{Cite journal | doi = 10.1089/rej.2009.0894 | issn = 1557-8577 | volume = 12 | pages = 283-288 | last = Cox | first = Lynne S. | coauthors = | title = Live fast, die young: new lessons in mammalian longevity | journal = Rejuvenation Research | date = 2009-08 | pmid = | pmc = }} </ref>