Anemia

Publication Title: 
Nutrition (Burbank, Los Angeles County, Calif.)

OBJECTIVES: The present study was aimed at assessing the effect of zinc- and micronutrient-rich food supplementation compared with ayurvedic zinc tablets on the blood levels of zinc and vitamin A in adolescent girls. METHODS: One hundred eighty apparently healthy schoolgirls (12.5 ± 0.85 y old) were recruited for a 10-wk intervention trial.

Author(s): 
Chiplonkar, Shashi A.
Kawade, Rama
Publication Title: 
Journal of General Internal Medicine

A 29-year-old man, who recently emigrated from India, presented with a 2-week history of abdominal pain, as well as nausea, constipation, and fatigue. He underwent removal of a parathyroid adenoma 6 weeks prior to admission and received a locally made Indian traditional medicine (Ayurveda) for pain control; however, this information was not initially available. He was instructed to take approximately 15 g/day. Initial evaluation revealed a normocytic anemia, but other workup including imaging and endoscopy was unrevealing.

Author(s): 
Pierce, J. Matthew R.
Estrada, Carlos A.
Mathews, Ronnie E.
Publication Title: 
Medical Science Monitor: International Medical Journal of Experimental and Clinical Research

BACKGROUND: Millions worldwide use Ayurvedic (traditional Indian) medicines. These medications are increasingly associated with lead poisoning, often accompanied by anemia. We compared the relative hematopoietic toxicity of Ayurvedic lead poisoning with a common form of occupational lead poisoning. MATERIAL/METHODS: We retrospectively studied 66 adult lead intoxications: 43 published Ayurvedic cases identified in published reports by searching MEDLINE (1966 to November 2005); 4 Ayurvedic patients seen at a referral center; and 19 lead paint intoxications from the same center.

Author(s): 
Kales, Stefanos N.
Christophi, Costas A.
Saper, Robert B.
Publication Title: 
Digestive Diseases and Sciences

The multifunctional pattern recognition scavenger receptors, SR-A and CD36, are predominantly expressed by lamina propria macrophages and considered important in innate immunity. We examined the role of these receptors in the pathophysiology of inflammatory bowel disease. Colitis was induced in wild type (WT), SRA(-/-), CD36(-/-), and SR-A/CD36 double deficient mice by administering DSS. DSS-induced moderately severe colitis in WT mice was manifested by weight loss, reduced hematocrit, and pathology.

Author(s): 
Oz, Helieh S.
Zhong, Jian
de Villiers, Willem J. S.
Publication Title: 
PloS One

Leishmania donovani is a parasite that causes visceral leishmaniasis by infecting and replicating in macrophages of the bone marrow, spleen, and liver. Severe anemia and leucopenia is associated with the disease. Although immune defense mechanisms against the parasite have been studied, we have a limited understanding of how L. donovani alters hematopoiesis. In this study, we used Syrian golden hamsters to investigate effects of L. donovani infection on erythropoiesis. Infection resulted in severe anemia and leucopenia by 8 weeks post-infection.

Author(s): 
Lafuse, William P.
Story, Ryan
Mahylis, Jocelyn
Gupta, Gaurav
Varikuti, Sanjay
Steinkamp, Heidi
Oghumu, Steve
Satoskar, Abhay R.
Publication Title: 
Pediatrics

BACKGROUND: Pneumonia is the leading cause of mortality in young children globally, and factors that affect tissue delivery of oxygen may affect outcomes of pneumonia. We studied whether altitude and anemia influence disease severity and outcomes in young children with World Health Organization-defined severe pneumonia.

Author(s): 
Moschovis, Peter P.
Banajeh, Salem
MacLeod, William B.
Saha, Samir
Hayden, Douglas
Christiani, David C.
Mino, Greta
Santosham, Mathuram
Thea, Donald M.
Qazi, Shamim
Hibberd, Patricia L.
Publication Title: 
AIDS alert
Publication Title: 
AIDS alert
Publication Title: 
Cadernos De Saúde Pública

Folate deficiency has been associated with anemia and other adverse outcomes in pregnancy such as neural tube defects. The current recommendations for prevention of such outcomes are difficult to achieve through diet only, and folic acid supplementation and food fortification are feasible public health strategies. However, it is necessary to determine the usual diet and supplement use among women of reproductive age, including an accurate assessment of other dietary micronutrients.

Author(s): 
Almeida, Lana Carneiro
Cardoso, Marly Augusto
Publication Title: 
Cellular & Molecular Immunology

Anemia and immunological dysfunction (i.e. immunosenescence) are commonly found in older subjects and nutritional approaches are sought to counteract these phenomena. Spirulina is a filamentous and multicellular bule-green alga capable of reducing inflammation and also manifesting antioxidant effects. We hypothesized that Spirulina may ameliorate anemia and immunosenescence in senior citizens with a history of anemia. We enrolled 40 volunteers of both sexes with an age of 50 years or older who had no history of major chronic diseases.

Author(s): 
Selmi, Carlo
Leung, Patrick S. C.
Fischer, Laura
German, Bruce
Yang, Chen-Yen
Kenny, Thomas P.
Cysewski, Gerry R.
Gershwin, M. Eric

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