Anesthetics, Local

Publication Title: 
Health Technology Assessment (Winchester, England)

BACKGROUND: Premature ejaculation (PE) is commonly defined as ejaculation with minimal sexual stimulation before, on or shortly after penetration and before the person wishes it. PE can be either lifelong and present since first sexual experiences (primary), or acquired (secondary), beginning later (Godpodinoff ML. Premature ejaculation: clinical subgroups and etiology. J Sex Marital Ther 1989;15:130-4). Treatments include behavioural and pharmacological interventions.

Author(s): 
Cooper, Katy
Martyn-St James, Marrissa
Kaltenthaler, Eva
Dickinson, Kath
Cantrell, Anna
Publication Title: 
Schmerz (Berlin, Germany)

Non-pharmaceutical procedures are increasingly being used in pediatric pain therapy in addition to pharmaceutical procedures and have a supporting function. This article describes the non-pharmaceutical procedures which have an influence on perioperative and posttraumatic pain in children and adolescents. Prerequisites for every adequate pain therapy are affection, imparting a feeling of security, distraction and the creation of a child-oriented environment. Topical analgesics are indicated for application to intact skin for surface anesthesia.

Author(s): 
Messerer, B.
Krauss-Stoisser, B.
Urlesberger, B.
Publication Title: 
The Annals of Pharmacotherapy

OBJECTIVE: To review the pharmacology and mechanisms by which local anesthetics cause allergic reactions. Recommendations concerning appropriate use of local anesthetics and alternative therapies in patients with documented local anesthetic allergies are given. DATA SOURCE: A MEDLINE search of English-language literature identified pertinent clinical studies, case reports, and reviews. The periods of review were Med1, 1990-present, and Med2, 1985-1989, using the MeSH terms drug hypersensitivity and anesthetics. References from the selected studies, case reports, and reviews were reviewed.

Author(s): 
Eggleston, S. T.
Lush, L. W.
Publication Title: 
American Family Physician

Knee osteoarthritis is a common disabling condition that affects more than one-third of persons older than 65 years. Exercise, weight loss, physical therapy, intra-articular corticosteroid injections, and the use of nonsteroidal anti-inflammatory drugs and braces or heel wedges decrease pain and improve function. Acetaminophen, glucosamine, ginger, S-adenosylmethionine (SAM-e), capsaicin cream, topical nonsteroidal anti-inflammatory drugs, acupuncture, and tai chi may offer some benefit. Tramadol has a poor trade-off between risks and benefits and is not routinely recommended.

Author(s): 
Ringdahl, Erika
Pandit, Sandesh
Publication Title: 
Quintessence International (Berlin, Germany: 1985)

OBJECTIVE: Burning mouth syndrome (BMS) is a common chronic pain condition that lacks a satisfactory treatment approach. This systematic review was designed to examine the effects of acupuncture or acupoint injection on the management of BMS and to evaluate the evidence supporting the use of acupuncture therapy for BMS in clinical practice.

Author(s): 
Yan, Zhimin
Ding, Ning
Hua, Hong
Publication Title: 
Health Technology Assessment (Winchester, England)

BACKGROUND: Premature ejaculation (PE) is commonly defined as ejaculation with minimal sexual stimulation before, on or shortly after penetration and before the person wishes it. PE can be either lifelong and present since first sexual experiences (primary), or acquired (secondary), beginning later (Godpodinoff ML. Premature ejaculation: clinical subgroups and etiology. J Sex Marital Ther 1989;15:130-4). Treatments include behavioural and pharmacological interventions.

Author(s): 
Cooper, Katy
Martyn-St James, Marrissa
Kaltenthaler, Eva
Dickinson, Kath
Cantrell, Anna
Publication Title: 
Electroencephalography and Clinical Neurophysiology
Author(s): 
Klemm, W. R.
Publication Title: 
Indian Journal of Physiology and Pharmacology

Substituted benzylamide derivatives of amino acylamide (compound A,B,C, & D) were found to be less potent local anaesthetics than lignocaine and procaine. However, the four compounds exhibited sedation without ptosis and reduced spontaneous locomotor activity better than methaqualone. Compound A alone antagonised methylamphetamine induced hypermotor activity. The test compounds potentiated hexobarbitone induced hypnosis. Three compounds antagonised calcium induced stoppage of isolated heart of frog.

Author(s): 
Sethi, O. P.
Gupta, M. V.
Bhatia, O. S.
Derasari, H. R.
Publication Title: 
Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica

The effect of oxatomide, an antiallergic drug, on the central and peripheral nervous systems were investigated, and the following results were obtained: Oxatomide at oral doses of 30-100 mg/kg produced little or no effect on the spontaneous and cooperative movements in mice, hexobarbital-induced hypnosis in mice, body temperature in rats, and did not induce muscle relaxation, the analgesic effect, anticonvulsive effects and anti-physostigmine effect. Oxatomide at doses of 300 mg/kg or more produced sedation followed by an increase in the responses to stimuli in mice and rats.

Author(s): 
Ohmori, K.
Ishii, H.
Shuto, K.
Nakamizo, N.
Publication Title: 
International Journal of Psychosomatics: Official Publication of the International Psychosomatics Institute
Author(s): 
Morse, D. R.
Schoor, R. S.
Cohen, B. B.

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