Antigens, CD24

Publication Title: 
Age (Dordrecht, Netherlands)

The B cell arm of adaptive immunity undergoes significant modifications with age. Elderly people are characterized by impaired B cell responses reflected in a reduced ability to effectively respond against viruses and bacteria. Alterations of immunity with advancing age (immunosenescence) have been widely studied in centenarians who are considered a good example of successful aging. In recent years, attention has shifted to centenarian offspring (CO) as a model of people genetically advantaged for healthy aging and longevity.

Author(s): 
Buffa, Silvio
PellicanÚ, Mariavaleria
Bulati, Matteo
Martorana, Adriana
Goldeck, David
Caruso, Calogero
Pawelec, Graham
Colonna-Romano, Giuseppina
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