Antineoplastic Agents

Publication Title: 
Klinische Padiatrie

Background: Chemotherapy-induced peripheral neuropathy is a frequent side-effect of drugs that are used in the treatment of cancer. Affected individuals can suffer from motor, sensory or autonomy nerve damage. Further medication is used for the treatment of CIPN which can cause further side-effects. Patients should be offered physical therapy treatment to relieve the symptoms. Objective: The aim of this article is to give an overview of available literature investigating physical therapy in CIPN in pediatric oncology.

Author(s): 
Jung, M.
Rein, N.
Fuchs, B.
Publication Title: 
Critical Reviews in Oncology/Hematology

Chemotherapy-induced peripheral neuropathy (CIPN) is a serious dose-limiting side-effect without any FDA-approved treatment option. Prior reviews focus mostly on pharmacological interventions, but nonpharmaceutical interventions have also been evaluated.

Author(s): 
Brami, Cloé
Bao, Ting
Deng, Gary
Publication Title: 
Journal of the National Cancer Institute. Monographs

BACKGROUND: The majority of breast cancer patients use complementary and/or integrative therapies during and beyond cancer treatment to manage symptoms, prevent toxicities, and improve quality of life. Practice guidelines are needed to inform clinicians and patients about safe and effective therapies. METHODS: Following the Institute of Medicine's guideline development process, a systematic review identified randomized controlled trials testing the use of integrative therapies for supportive care in patients receiving breast cancer treatment.

Author(s): 
Greenlee, Heather
Balneaves, Lynda G.
Carlson, Linda E.
Cohen, Misha
Deng, Gary
Hershman, Dawn
Mumber, Matthew
Perlmutter, Jane
Seely, Dugald
Sen, Ananda
Zick, Suzanna M.
Tripathy, Debu
Society for Integrative Oncology
Publication Title: 
Journal of the National Cancer Institute. Monographs

BACKGROUND: The majority of breast cancer patients use complementary and/or integrative therapies during and beyond cancer treatment to manage symptoms, prevent toxicities, and improve quality of life. Practice guidelines are needed to inform clinicians and patients about safe and effective therapies. METHODS: Following the Institute of Medicine's guideline development process, a systematic review identified randomized controlled trials testing the use of integrative therapies for supportive care in patients receiving breast cancer treatment.

Author(s): 
Greenlee, Heather
Balneaves, Lynda G.
Carlson, Linda E.
Cohen, Misha
Deng, Gary
Hershman, Dawn
Mumber, Matthew
Perlmutter, Jane
Seely, Dugald
Sen, Ananda
Zick, Suzanna M.
Tripathy, Debu
Society for Integrative Oncology
Publication Title: 
The Cochrane Database of Systematic Reviews

BACKGROUND: This is the second update of the review first published in the Cochrane Database of Systematic Reviews in 2009, Issue 1. Epithelial ovarian cancer is diagnosed in over 200,000 women worldwide each year. Ten to 20% of women are diagnosed early, when there is still a good possibility of cure. The treatment of early-stage (stage I and IIa) disease involves surgery to remove the disease, often followed by chemotherapy (adjuvant chemotherapy).

Author(s): 
Lawrie, Theresa A.
Winter-Roach, Brett A.
Heus, Pauline
Kitchener, Henry C.
Publication Title: 
Journal of Pediatric Oncology Nursing: Official Journal of the Association of Pediatric Oncology Nurses

Chemotherapy-induced nausea and vomiting (CINV) continues to be a common symptom experienced by children undergoing cancer treatment despite the use of contemporary antiemetics. Integrative therapeutic approaches in addition to standard pharmacologic antiemetic regimes offer potential to control CINV. The purpose of this review was to identify current evidence on integrative therapeutic approaches for the control of CINV in children with cancer. Online search engines (PubMed, CINAHL, PsychINFO) were queried using MESH terms.

Author(s): 
Momani, Tha'er G.
Berry, Donna L.
Publication Title: 
Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer

PURPOSE: We aimed to update the 2011 recommendations for the prevention and treatment of anticipatory nausea and vomiting in children and adults receiving chemotherapy. METHODS: The original systematic literature search was updated.

Author(s): 
Dupuis, L. Lee
Roscoe, Joseph A.
Olver, Ian
Aapro, Matti
Molassiotis, Alexander
Publication Title: 
Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology

PURPOSE: Adverse effects of chemotherapy can be severe and can have a significant impact on a person's quality of life. With chemotherapy treatment increasingly administered in the ambulatory setting, there is a need for patients to be informed about effective self-care strategies to manage treatment adverse effects. Advice for patients needs to be based on evidence.

Author(s): 
Lotfi-Jam, Kerryann
Carey, Mariko
Jefford, Michael
Schofield, Penelope
Charleson, Catherine
Aranda, Sanchia
Publication Title: 
European Journal of Cancer Care

To systematically review the research evidence on the effectiveness of hypnosis for cancer chemotherapy-induced nausea and vomiting (CINV). A comprehensive search of major biomedical databases including MEDLINE, EMBASE, ClNAHL, PsycINFO and the Cochrane Library was conducted. Specialist complementary and alternative medicine databases were searched and efforts were made to identify unpublished and ongoing research. Citations were included from the databases' inception to March 2005. Randomized controlled trials (RCTs) were appraised and meta-analysis undertaken.

Author(s): 
Richardson, J.
Smith, J. E.
McCall, G.
Richardson, A.
Pilkington, K.
Kirsch, I.
Publication Title: 
International Journal of Oral and Maxillofacial Surgery

Head and neck cancer represents one of the main oncological problems. Its treatment, radiotherapy and chemotherapy leads to mucositis, and other side effects. The authors reviewed high-quality evidence published over the last 25 years on the treatment of cancer treatment-induced oral mucositis. A Medline search for double blind randomized controlled clinical trials between 1985 and 2010 was carried out. The keywords were oral mucositis, radiotherapy, chemotherapy, and head and neck.

Author(s): 
Rodríguez-Caballero, A.
Torres-Lagares, D.
Robles-García, M.
Pachón-Ibáñez, J.
González-Padilla, D.
Gutierrez-Perez, J. L.

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