Heparan Sulfate Proteoglycans

Publication Title: 
Aging Cell

Aging poses one of the largest risk factors for the development of cardiovascular disease. The increased propensity toward vascular pathology with advancing age maybe explained, in part, by a reduction in the ability of circulating endothelial progenitor cells to contribute to vascular repair and regeneration. Although there is evidence to suggest that colony forming unit-Hill cells and circulating angiogenic cells are subject to age-associated changes that impair their function, the impact of aging on human outgrowth endothelial cell (OEC) function has been less studied.

Author(s): 
Williamson, Kate A.
Hamilton, Andrew
Reynolds, John A.
Sipos, Peter
Crocker, Ian
Stringer, Sally E.
Alexander, Yvonne M.
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