Hot Flashes

Publication Title: 
The Cochrane Database of Systematic Reviews

BACKGROUND: Chinese herbal medicine (CHM) usage is expected to increase as women suffering from menopausal symptoms are seeking alternative therapy due to concerns from the adverse effects (AEs) associated with hormone therapy (HT). Scientific evidence for their effectiveness and safety is needed. OBJECTIVES: To evaluate the effectiveness and safety of CHM in the treatment of menopausal symptoms.

Zhu, Xiaoshu
Liew, Yuklan
Liu, Zhao Lan
Publication Title: 
Cancer Nursing

BACKGROUND: Evidence regarding the effects of acupuncture on hot flashes in breast cancer survivors is conflicting. Little is known about the intermediate-term effects of acupuncture on hot flashes and other menopause-related symptoms in breast cancer survivors. OBJECTIVE: The objective of this study was to evaluate the short-term and intermediate-term effects of acupuncture on menopause-related symptoms and particularly on hot flashes in breast cancer survivors.

Chiu, Hsiao-Yean
Shyu, Yuh-Kae
Chang, Pi-Chen
Tsai, Pei-Shan
Publication Title: 
Journal of Cancer Research and Therapeutics

BACKGROUND: Acupuncture is applied worldwide in treating hot flashes (HFs), which may be a common complication experienced by women with breast cancer (BC). Although researches associated with the effect of acupuncture for HFs have been done by many people, there is a lack of comprehensive evaluation of the effect of this therapy. OBJECTIVE: The aim of this systematic review is to assess the effectiveness of acupuncture for HFs in women with BC.

Chen, Yu-Pei
Liu, Tong
Peng, Yuan-Yuan
Wang, Yan-Ping
Chen, Huan
Fan, Yi-Fan
Zhang, Li
Publication Title: 
American Family Physician

The results of large clinical trials have led physicians and patients to question the safety of hormone therapy for menopause. In the past, physicians prescribed hormone therapy to improve overall health and prevent cardiac disease, as well as for symptoms of menopause. Combined estrogen/progestogen therapy, but not estrogen alone, increases the risk of breast cancer when used for more than three to five years.

Hill, D. Ashley
Crider, Mark
Hill, Susan R.
Publication Title: 
Breast Cancer Research and Treatment

PURPOSE: To access frequency and severity of adverse effects (AE) of non-hormonal drugs (NHD) for hot flashes in breast cancer survivors compared to controls and analyze adverse-effect risk by reviewing published randomized trials. METHODS: Cochrane Central Register for Controlled Trials, Embase, Medline, PsycINFO and PubMed databases were searched. Trials were included where participants were survivors of breast cancer suffering from hot flashes, treatment included self-administered venlafaxine, gabapentin or clonidine, and AE were reported. AE frequency and severity were graded.

Hervik, Jill Brook
Stub, Trine
Publication Title: 
Systematic Reviews

BACKGROUND: Breast and prostate cancers are the most commonly diagnosed non-dermatologic malignancies in Canada. Agents including endocrine therapies (e.g., aromatase inhibitors, gonadotrophin-releasing hormone analogs, anti-androgens, tamoxifen) and chemotherapy have improved survival for both conditions. As endocrine manipulation is a mainstay of treatment, it is not surprising that hot flashes are a common and troublesome adverse effect. Hot flashes can cause chills, night sweats, anxiety, and insomnia, lessening patients' quality of life.

Hutton, Brian
Yazdi, Fatemeh
Bordeleau, Louise
Morgan, Scott
Cameron, Chris
Kanji, Salmaan
Fergusson, Dean
Tricco, Andrea
Straus, Sharon
Skidmore, Becky
Hersi, Mona
Pratt, Misty
Mazzarello, Sasha
Brouwers, Melissa
Moher, David
Clemons, Mark
Publication Title: 
Systematic Reviews

BACKGROUND: Vasomotor symptoms such as hot flashes and night sweats are a common concern of perimenopausal and postmenopausal women and are associated with a decreased quality of life. These symptoms can be effectively managed with hormone therapy, but safety concerns limit its use. Thus, understanding the effectiveness of nonpharmacologic therapies such as acupuncture or yoga is critical to managing these common symptoms in older women.

Goldstein, Karen M.
McDuffie, Jennifer R.
Shepherd-Banigan, Megan
Befus, Deanna
Coeytaux, Remy R.
Van Noord, Megan G.
Goode, Adam P.
Masilamani, Varsha
Adam, Soheir
Nagi, Avishek
Williams, John W.
Publication Title: 
Menopause (New York, N.Y.)

OBJECTIVE: To update and expand The North American Menopause Society's evidence-based position on nonhormonal management of menopause-associated vasomotor symptoms (VMS), previously a portion of the position statement on the management of VMS. METHODS: NAMS enlisted clinical and research experts in the field and a reference librarian to identify and review available evidence. Five different electronic search engines were used to cull relevant literature. Using the literature, experts created a document for final approval by the NAMS Board of Trustees.

Publication Title: 

Hot flashes (HFs) are a common side effect of cancer treatment. The purpose of this systematic review was to evaluate evidence related to the use of acupuncture for HFs in cancer patients. EMBASE, MEDLINE, Cochrane (all databases), PubMed, the Cumulative Index to Nursing and Allied Health Literature, and Scopus were searched from their inception through December 2014. Included studies had to be randomized controlled trials with a usual-care and/or placebo comparison group that investigated acupuncture to treat HFs in cancer patients. No language limits were applied.

Garcia, M. Kay
Graham-Getty, Leslie
Haddad, Robin
Li, Yisheng
McQuade, Jennifer
Lee, Richard T.
Spano, Michael
Cohen, Lorenzo
Publication Title: 
Breast Cancer Research and Treatment

Patient-centered decision making about hot flash treatments often incorporates a balance of efficacy and side effects in addition to patient preference. This systematic review examines randomized controlled trials (RCTs) comparing at least two non-hormonal hot flash treatments in breast cancer survivors. In July 2015, PubMed, SCOPUS, CINAHL, Cochrane, and Web of Science databases were searched for RCTs comparing active, non-hormonal hot flash treatments in female breast cancer survivors. Thirteen trials were included after identifying 906 potential studies.

Johns, Claire
Seav, Susan M.
Dominick, Sally A.
Gorman, Jessica R.
Li, Hongying
Natarajan, Loki
Mao, Jun James
Irene Su, H.


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