Hypericum

Publication Title: 
Journal of Affective Disorders

BACKGROUND: In 2001, the Canadian Psychiatric Association and the Canadian Network for Mood and Anxiety Treatments (CANMAT) partnered to produce evidence-based clinical guidelines for the treatment of depressive disorders. A revision of these guidelines was undertaken by CANMAT in 2008-2009 to reflect advances in the field. There is widespread interest in complementary and alternative medicine (CAM) therapies in the treatment of major depressive disorder (MDD). METHODS: The CANMAT guidelines are based on a question-answer format to enhance accessibility to clinicians.

Author(s): 
Ravindran, Arun V.
Lam, Raymond W.
Filteau, Marie J.
Lespérance, François
Kennedy, Sidney H.
Parikh, Sagar V.
Patten, Scott B.
Canadian Network for Mood and Anxiety Treatments (CANMAT)
Publication Title: 
Current Opinion in Psychiatry

PURPOSE OF REVIEW: There is well documented evidence for the increasing widespread use of complementary and alternative medicine in the treatment of physical and psychiatric symptoms and disorders within Western populations. Here we provide a review of the recent literature on evidence for using such interventions in the treatment of anxiety and depression. RECENT FINDINGS: With regard to herbal treatments, kava is effective in reducing anxiety symptoms and St John's wort in treating mild to moderate depression.

Author(s): 
van der Watt, Gill
Laugharne, Jonathan
Janca, Aleksandar
Publication Title: 
Homeopathy: The Journal of the Faculty of Homeopathy

BACKGROUND: Hypericum perforatum (St. John's Wort) has been used for a variety of medicinal indications. Most recent research has focussed on its use in herbal form for depression, but its claimed analgesic and anti-inflammatory properties in homeopathic form have also led to a number of studies in patients with acute pain conditions. This systematic review overviews the literature on the use of St. John's Wort for pain conditions in homeopathic dental practice.

Author(s): 
Raak, Christa
Büssing, Arndt
Gassmann, Georg
Boehm, Katja
Ostermann, Thomas
Publication Title: 
The Journal of Clinical Psychiatry

BACKGROUND: This article is a critical review of the efficacy of selected alternative treatments for unipolar depression including exercise, stress management techniques, acupuncture, St. John's wort, bright light, and sleep deprivation. Issues related to women across the life span, including pregnancy and lactation, are highlighted. DATA SOURCES: Evidence of efficacy is based on randomized controlled trials. A distinction is made between studies that address depressive symptoms and studies that address depressive disorders.

Author(s): 
Manber, Rachel
Allen, John J. B.
Morris, Margaret E.
Morris, Margaret M.
Publication Title: 
Current Opinion in Psychiatry

PURPOSE OF REVIEW: There is well documented evidence for the increasing widespread use of complementary and alternative medicine in the treatment of physical and psychiatric symptoms and disorders within Western populations. Here we provide a review of the recent literature on evidence for using such interventions in the treatment of anxiety and depression. RECENT FINDINGS: With regard to herbal treatments, kava is effective in reducing anxiety symptoms and St John's wort in treating mild to moderate depression.

Author(s): 
van der Watt, Gill
Laugharne, Jonathan
Janca, Aleksandar
Publication Title: 
Current Opinion in Psychiatry

PURPOSE OF REVIEW: There is well documented evidence for the increasing widespread use of complementary and alternative medicine in the treatment of physical and psychiatric symptoms and disorders within Western populations. Here we provide a review of the recent literature on evidence for using such interventions in the treatment of anxiety and depression. RECENT FINDINGS: With regard to herbal treatments, kava is effective in reducing anxiety symptoms and St John's wort in treating mild to moderate depression.

Author(s): 
van der Watt, Gill
Laugharne, Jonathan
Janca, Aleksandar
Publication Title: 
Journal of Affective Disorders

A growing number of patients with mood disorders are using complementary and alternative medicine (CAM) interventions. In this paper, we review the published scientific evidence on the benefits and risks of CAM for the treatment of patients with bipolar disorder. Since very few studies of CAM have involved patients with bipolar disorder, most available evidence is derived from trials conducted in patients with major depressive disorder. The use of omega-3 fatty acids has been studied in two controlled studies in bipolar disorder while St.

Author(s): 
Andreescu, Carmen
Mulsant, Benoit H.
Emanuel, James E.
Publication Title: 
Journal of Affective Disorders

BACKGROUND: In 2001, the Canadian Psychiatric Association and the Canadian Network for Mood and Anxiety Treatments (CANMAT) partnered to produce evidence-based clinical guidelines for the treatment of depressive disorders. A revision of these guidelines was undertaken by CANMAT in 2008-2009 to reflect advances in the field. There is widespread interest in complementary and alternative medicine (CAM) therapies in the treatment of major depressive disorder (MDD). METHODS: The CANMAT guidelines are based on a question-answer format to enhance accessibility to clinicians.

Author(s): 
Ravindran, Arun V.
Lam, Raymond W.
Filteau, Marie J.
Lespérance, François
Kennedy, Sidney H.
Parikh, Sagar V.
Patten, Scott B.
Canadian Network for Mood and Anxiety Treatments (CANMAT)
Publication Title: 
Pharmacoepidemiology and Drug Safety

PURPOSE: The purpose of this report is to characterize reports to poison control centers (PCCs) involving two widely used herbal dietary supplements (HDSs), Echinacea, and St. John's wort (SJW). METHODS: We purchased data from the American Association of Poison Control Center's (AAPCC) toxic exposure surveillance system (TESS(R)) on reports made to PCCs in 2001 involving Echinacea or SJW. Analyses were limited to those cases in which Echinacea or SJW were the only associated products, and in which these HDSs were deemed primary to observed adverse effects.

Author(s): 
Gryzlak, Brian M.
Wallace, Robert B.
Zimmerman, M. Bridget
Nisly, Nicole L.
Publication Title: 
Journal of Natural Products

Flavonoids have been recognized as the active ingredients of many medicinal plant extracts due to interactions with proteins via phenolic groups and low toxicity. Here, we report the investigation of the flavonoid core as a potential new scaffold for the development of opioid receptor ligands. Biological results suggest that stereochemistry of the C2 and C3 positions is important for antagonist activity and selectivity. Our results also suggest that the actions of Hypericum perforatum may be mediated in part by opioid receptors.

Author(s): 
Katavic, Peter L.
Lamb, Kenneth
Navarro, Hernan
Prisinzano, Thomas E.

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