Publication Title: 

BACKGROUND: Hypertension is a risk factor for cardiovascular disease, and the prevalence of hypertension tends to increase with age. Current treatments for hypertension have adverse side effects and poor adherence. The purpose of this study is to evaluate the effects of moxibustion on blood pressure in individuals with pre- or stage I hypertension. METHODS/DESIGN: Forty-five subjects with pre- or stage I hypertension will be randomized into three groups: treatment group A (2 times/week), treatment group B (3 times/week), and the control group (non-treated group).

Shin, Kyung-Min
Park, Ji-Eun
Liu, Yan
Jung, Hee-Jung
Jung, So-Young
Lee, Min-Hee
Kang, Kyung-Won
Yook, Tae-Han
Choi, Sun-Mi
Publication Title: 

Many antihypertensive medications and lifestyle changes are proven to reduce blood pressure. Over the past few decades, numerous additional modalities have been evaluated in regard to their potential blood pressure-lowering abilities. However, these nondietary, nondrug treatments, collectively called alternative approaches, have generally undergone fewer and less rigorous trials.

Brook, Robert D.
Appel, Lawrence J.
Rubenfire, Melvyn
Ogedegbe, Gbenga
Bisognano, John D.
Elliott, William J.
Fuchs, Flavio D.
Hughes, Joel W.
Lackland, Daniel T.
Staffileno, Beth A.
Townsend, Raymond R.
Rajagopalan, Sanjay
American Heart Association Professional Education Committee of the Council for High Blood Pressure Research, Council on Cardiovascular and Stroke Nursing, Council on Epidemiology and Prevention, and Council on Nutrition, Physical Activity
Publication Title: 
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology

Acupuncture or electroacupuncture (EA) potentially offers a nonpharmacological approach to reduce high blood pressure (BP). However, ~70% of the patients and animal subjects respond to EA, while 30% do not. EA acts, in part, through an opioid mechanism in the rostral ventrolateral medulla (rVLM) to inhibit sympathoexcitatory reflexes induced by gastric distention. CCK-8 opposes the action of opioids during analgesia. Therefore, we hypothesized that CCK-8 in the rVLM antagonizes EA modulation of sympathoexcitatory cardiovascular reflex responses.

Li, Min
Tjen-A-Looi, Stephanie C.
Guo, Zhi-Ling
Longhurst, John C.
Publication Title: 
Annals of Laboratory Medicine
Yang, John Jeongseok
Kwon, Tae Yoon
Seo, Mi Jeong
Nam, You Sun
Han, Chung Soo
Lee, Hee-Joo
Publication Title: 
International Journal of Cardiology

BACKGROUND: To systematically assess the current clinical evidence of acupuncture for hypertension. SEARCH STRATEGY: The PubMed, EMBASE, Chinese Biomedical Literature Database (CBM), Chinese National Knowledge Infrastructure (CNKI), Chinese Scientific Journal Database (VIP), and Wan-fang Data in the Cochrane Library were searched until January, 2013. All the randomized controlled trials (RCTs) based on acupuncture compared with western medicine, sham acupuncture or lifestyle intervention in patients with hypertension were included.

Wang, Jie
Xiong, Xingjiang
Liu, Wei
Publication Title: 
Acupuncture in Medicine: Journal of the British Medical Acupuncture Society

This report describes the regular use of acupuncture treatments for a patient with hypertension who could not tolerate the side effects of the antihypertensive agents. The patient received 60 acupuncture treatments in the course of 12 weeks, during which time his overall wellbeing improved, his blood pressure reduced and the side effects of antihypertensive drugs were removed.

Zhang, Lili
Shen, Pengfei
Wang, Shu
Publication Title: 

BACKGROUND: Several studies using acupuncture to treat essential hypertension have been carried out. However, whether acupuncture is efficacious for hypertension is still controversial. Therefore, this trial aims to evaluate the efficacy and safety of acupuncture for patients with mild hypertension. METHODS/DESIGN: This is a large scale, open-label, multicenter, randomized controlled clinical trial with four parallel arms. We will recruit 428 hypertensive patients with systolic blood pressure (SBP) between 140 and 159 mmHg, diastolic blood pressure (DBP) between 90 and 99 mmHg.

Li, Juan
Zheng, Hui
Zhao, Ling
Li, Ying
Zhang, Yan
Chang, Xiao-rong
Wang, Rui-hui
Shi, Jing
Cui, Jin
Huang, Yin-lan
Li, Xiang
Chen, Jie
Li, De-hua
Liang, Fan-Rong
Publication Title: 
Complementary Therapies in Medicine

The objective of this review was to assess the current clinical evidence of moxibustion for essential hypertension (EH). 7 electronic databases were searched until March 2013. Randomized clinical trials testing moxibustion, or combined with antihypertensive drugs, against antihypertensive drugs alone were included. Study selection, data extraction, quality assessment, and data analyses were conducted according to the Cochrane standards. Finally, 5 randomized trials were included. The methodological quality of the included trials was evaluated as generally low.

Xiong, Xingjiang
Liu, Wei
Yang, Xiaochen
Feng, Bo
Wang, Jie


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