Mood Disorders

Publication Title: 

Fibromyalgia (FM) is thought to involve abnormalities in central pain processing. Recent studies involving small samples have suggested alterations in gray matter volume (GMV) in brains of FM patients. Our objective was to verify these findings in a somewhat larger sample using voxel-based morphometry (VBM), while controlling for the presence of affective disorders (AD). T1-weighted magnetic resonance image (MRI) brain scans were obtained on 29 FM patients with AD, 29 FM patients without AD, and 29 age-matched healthy controls (HCs) using a 3T scanner.

Hsu, Michael C.
Harris, Richard E.
Sundgren, Pia C.
Welsh, Robert C.
Fernandes, Carlo R.
Clauw, Daniel J.
Williams, David A.
Publication Title: 
The British Journal of Psychiatry: The Journal of Mental Science

BACKGROUND: Depression measures that include somatic symptoms may inflate severity estimates among medically ill patients, including those with cardiovascular disease. AIMS: To evaluate whether people receiving in-patient treatment following acute myocardial infarction (AMI) had higher somatic symptom scores on the Beck Depression Inventory-II (BDI-II) than a non-medically ill control group matched on cognitive/affective scores.

Thombs, Brett D.
Ziegelstein, Roy C.
Pilote, Louise
Dozois, David J. A.
Beck, Aaron T.
Dobson, Keith S.
Fuss, Samantha
de Jonge, Peter
Grace, Sherry L.
Stewart, Donne E.
Ormel, Johan
Abbey, Susan E.
Publication Title: 
Journal of Psychoactive Drugs

Mindfulness training may disrupt the risk chain of stress-precipitated alcohol relapse. In 2008, 53 alcohol-dependent adults (mean age = 40.3) recruited from a therapeutic community located in the urban southeastern U.S. were randomized to mindfulness training or a support group. Most participants were male (79.2%), African American (60.4%), and earned less than $20,000 annually (52.8%). Self-report measures, psychophysiological cue-reactivity, and alcohol attentional bias were analyzed via repeated measures ANOVA. Thirty-seven participants completed the interventions.

Garland, Eric L.
Gaylord, Susan A.
Boettiger, Charlotte A.
Howard, Matthew O.
Publication Title: 
The Journal of Pain: Official Journal of the American Pain Society

A burgeoning body of evidence supports the efficacy and elucidates the mechanisms of placebo analgesia. Debate persists, however, concerning their ethical use, with many of the present arguments being philosophically based. The present web-based study empirically investigated the acceptability of an analgesic placebo treatment. Participants (103) responded to vignettes depicting patients receiving a placebo analgesic. We experimentally manipulated: 1) placebo treatment instructions (level of deception); 2) treatment outcome; and 3) patients' pain severity.

Kisaalita, Nkaku R.
Roditi, Daniela
Robinson, Michael E.
Publication Title: 
European Journal of Pain (London, England)

Pain has both sensory-discriminative and emotional-affective dimensions. Previous studies demonstrate that electroacupuncture (EA) alleviates the sensory dimension but do not address the affective. An inflammatory pain rat model, produced by a complete Freund adjuvant (CFA) injection into the hind paw, was combined with a conditioned place avoidance (CPA) test to determine whether EA inhibits spontaneous pain-induced affective response and, if so, to study the possibility that rostral anterior cingulate cortex (rACC) opioids underlie this effect.

Zhang, Y.
Meng, X.
Li, A.
Xin, J.
Berman, B. M.
Lao, L.
Tan, M.
Ren, K.
Zhang, R.-X.
Publication Title: 
Alternative Therapies in Health and Medicine

CONTEXT: Although epidemiological studies have reported protective effects of religion and spirituality on mental health, it is unknown whether spirituality can be used as an intervention to improve psychological well-being. OBJECTIVE: To evaluate the efficacy of a home study-based spirituality program on mood disturbance in emotionally distressed patients.

Moritz, Sabine
Quan, Hude
Rickhi, Badri
Liu, Mingfu
Angen, Maureen
Vintila, Renata
Sawa, Russell
Soriano, Jeanette
Toews, John
Publication Title: 
Alternative Therapies in Health and Medicine

CONTEXT: With the current globalization of the world's economy and demands for enhanced performance, stress is present universally. Life's stressful events and daily stresses cause both deleterious and cumulative effects on the human body. The practice of meditation might offer a way to relieve that stress. OBJECTIVE: The research team intended to study the effects of meditation on stress-induced changes in physiological parameters, cognitive functions, intelligence, and emotional quotients. METHODS: The research team conducted the study in two phases, with a month between them.

Singh, Yogesh
Sharma, Ratna
Talwar, Anjana
Publication Title: 
Palliative Medicine

A randomised controlled pilot study was carried out to examine the effects of adjunctive aromatherapy massage on mood, quality of life and physical symptoms in patients with cancer attending a specialist unit. Participants were randomised to conventional day care alone or day care plus weekly aromatherapy massage using a standardised blend of oils for four weeks. At baseline and at weekly intervals, patients rated their mood, quality of life and the intensity and bother of two symptoms most important to them. Forty-six patients were recruited to the study.

Wilcock, Andrew
Manderson, CathAnn
Weller, Rebecca
Walker, George
Carr, Diane
Carey, Anne-Marie
Broadhurst, Debbie
Mew, June
Ernst, Edzard
Publication Title: 

BACKGROUND: This chapter aims to differentiate between "alternative" therapies, often promoted falsely as viable options to mainstream lung cancer treatment, and complementary therapies, adjunctive, effective techniques that treat symptoms associated with cancer and its mainstream treatment, and to describe the evidence base for use of complementary therapies. METHODS AND DESIGN: A multidisciplinary panel of experts in oncology and integrative medicine evaluated the evidence for complementary (not alternative) therapies in the care of patients with lung cancer.

Cassileth, Barrie R.
Deng, Gary E.
Gomez, Jorge E.
Johnstone, Peter A. S.
Kumar, Nagi
Vickers, Andrew J.
American College of Chest Physicians
Publication Title: 
Autonomic Neuroscience: Basic & Clinical

OBJECTIVES: The purpose of this study was to examine the effect of repeated effleurage massage treatments compared with a visit control group on circulating lymphocytes by studying the number and activity of peripheral blood NK cells, CD4+ and CD8+ T cells in women with breast cancer. Furthermore, the effect of repeated effleurage massage treatments on the levels of cortisol in saliva and oxytocin in plasma as well as degree anxiety, depression and quality of life was studied. DESIGN: A single centre, prospective, randomized, controlled trial.

Billhult, A.
Lindholm, C.
Gunnarsson, Ronny
Stener-Victorin, E.


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