Oocytes

Publication Title: 
Medical Hypotheses

Merkel cells are located in glabrous and hairy skin and in some mucosa. They are characterized by dense-core secretory granules and cytoskeletal filaments. They are attached to neighboring keratinocytes by desmosomes and contain melanosomes similar to keratinocytes. They are excitable cells in close contact with sensory nerve endings but their function is still unclear. In this review, following roles are attributed for the first time to the Merkel cells: (1) melanosomes in Merkel cells may be involved in mammalian magnetoreception.

Author(s): 
Irmak, M. Kemal
Publication Title: 
Medical Hypotheses

Merkel cells are located in glabrous and hairy skin and in some mucosa. They are characterized by dense-core secretory granules and cytoskeletal filaments. They are attached to neighboring keratinocytes by desmosomes and contain melanosomes similar to keratinocytes. They are excitable cells in close contact with sensory nerve endings but their function is still unclear. In this review, following roles are attributed for the first time to the Merkel cells: (1) melanosomes in Merkel cells may be involved in mammalian magnetoreception.

Author(s): 
Irmak, M. Kemal
Publication Title: 
Human Reproduction (Oxford, England)

The aim of the present study was to evaluate the anaesthetic effect during oocyte aspiration of a paracervical block (PCB) in combination with either electro-acupuncture (EA) or intravenous alfentanil. In all, 150 women undergoing in-vitro fertilization (IVF) and embryo transfer were randomized to receive either EA plus PCB or alfentanil plus PCB. Visual analogue scales (VAS) were used to evaluate subjective experiences during oocyte aspiration, and IVF outcome parameters were recorded.

Author(s): 
Stener-Victorin, E.
Waldenström, U.
Nilsson, L.
Wikland, M.
Janson, P. O.
Publication Title: 
Human Reproduction (Oxford, England)

BACKGROUND: In a previous study on the effect of electro-acupuncture (EA) in combination with a paracervical block (PCB) as an analgesic method during oocyte aspiration in IVF treatment, EA appeared to increase the pregnancy rate. This study was designed to test the hypothesis that EA as an analgesic during oocyte aspiration would result in: (i) a better IVF pregnancy rate than with alfentanil; (ii) peroperative analgesia that was as good as that produced by alfentanil; (iii) less postoperative abdominal pain, nausea and stress; and (iv) a reduction in the use of additional analgesics.

Author(s): 
Stener-Victorin, Elisabet
Waldenström, Urban
Wikland, Matts
Nilsson, Lars
Hägglund, Leif
Lundeberg, Thomas
Publication Title: 
Human Reproduction (Oxford, England)

BACKGROUND: Acupuncture previously has proved its pain-relieving effect for ovum pick-up (OPU). The analgesic effect of electro-acupuncture (EA) was evaluated when EA was applied for only a few minutes prior to OPU in an attempt to make EA more attractive for clinical use. METHODS: Two hundred patients undergoing OPU were randomized prospectively using sealed, unlabelled envelopes, to receive pain relief with either EA in combination with a paracervical block (PCB) (n = 100) or conventional medical analgesia (CMA) in combination with a PCB (n = 100).

Author(s): 
Humaidan, Peter
Stener-Victorin, Elisabet
Publication Title: 
Human Reproduction (Oxford, England)

OBJECTIVE: The primary objective of the present review was to determine what pain-relieving effect had been reported for acupuncture and other conscious sedation methods in assisted reproduction therapy since 1990. The secondary objective was to determine pregnancy rates, when possible. METHODS: The data source was the Medline database of the National Library of Medicine covering the period January 1990-January 2004. Bibliographies of relevant publications and review articles were scanned.

Author(s): 
Stener-Victorin, Elisabet
Publication Title: 
Human Reproduction (Oxford, England)
Author(s): 
Renckens, C.
Publication Title: 
Human Reproduction (Oxford, England)

BACKGROUND: The primary aims were to compare the pain-relieving effect and post-operative well-being between electro-acupuncture analgesia (EA) and conventional analgesia (CA) comprising opiates. Further aims were to compare time for mobilization, and costs for time and drug consumption. METHODS: In all, 160 women undergoing IVF were randomized, according to a computer-generated list, to EA or CA. Well-being was evaluated with the State Trait Anxiety Inventory (STAI). Pain and subjective expectations and experiences were recorded on a visual analogue scale (VAS).

Author(s): 
Gejervall, Ann-Louise
Stener-Victorin, Elisabet
Möller, Anders
Janson, Per Olof
Werner, Charlotte
Bergh, Christina
Publication Title: 
Human Reproduction (Oxford, England)

BACKGROUND: The aim of this study was to compare the pain-relieving effect and the subjective well-being between auricular electro-acupuncture (EA) analgesia, auricular acupuncture (A) and conventional analgesia with remifentanil (CO).

Author(s): 
Sator-Katzenschlager, Sabine M.
Wölfler, Monika M.
Kozek-Langenecker, Sibylle A.
Sator, Kathrin
Sator, Paul-G.
Li, Borwen
Heinze, Georg
Sator, Michael O.
Publication Title: 
Cellular and molecular life sciences: CMLS

Hypoxic/ischemic disruption of ionic homeostasis is a critical trigger of neuronal injury/death in the brain. There is, however, no promising strategy against such pathophysiologic change to protect the brain from hypoxic/ischemic injury. Here, we present a novel finding that activation of delta-opioid receptors (DOR) reduced anoxic Na+ influx in the mouse cortex, which was completely blocked by DOR antagonism with naltrindole.

Author(s): 
Kang, Xuezhi
Chao, Dongman
Gu, Quanbao
Ding, Guanghong
Wang, Yingwei
Balboni, Gianfranco
Lazarus, Lawrence H.
Xia, Ying

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