Plant Stems

Publication Title: 
CNS & neurological disorders drug targets

Aging, the major cause of several ailments has led to intense exploration of potential drugs that delay aging and its associated effects. We mined the information on traditional Indian medicines and identified an iridoid, 10-O-trans-p-Coumaroylcatalpol (OCC), a major ingredient of Premna integrifolia Linn. (syn: Premna serratifolia). OCC forms an important constituent of famous herbal formulation 'Dashmula', a ten herb formulation, commonly used for its various medicinal properties. Employing model system C.

Author(s): 
Shukla, Virendra
Phulara, Suresh C.
Yadav, Deepti
Tiwari, Sudeep
Kaur, Supinder
Gupta, M. M.
Nazir, Aamir
Pandey, Rakesh
Publication Title: 
Pharmaceutical Biology

CONTEXT: The genus Urtica has been known since ancient times. It has known to be useful for the treatment of different human ailments. OBJECTIVE: The present work evaluated the neuropharmacological effects of a hydroalcoholic extract of Urtica circularis (Hicken) Sorarú (Urticaceae). materials and method: The effect on central nervous system of U.

Author(s): 
Anzoise, María Laura
Marrassini, Carla
Ferraro, Graciela
Gorzalczany, Susana
Publication Title: 
Malaria Journal

BACKGROUND: Artemisinin is the current drug of choice for treatment of malaria and a number of other diseases. It is obtained from the annual herb, Artemisia annua and some microbial sources by genetic engineering. There is a great concern that the artemisinin production at current rate will not meet the increasing demand by the pharmaceutical industry, so looking for additional sources is imperative.

Author(s): 
Mannan, Abdul
Ahmed, Ibrar
Arshad, Waheed
Asim, Muhammad F.
Qureshi, Rizwana A.
Hussain, Izhar
Mirza, Bushra
Publication Title: 
Acta Medica Indonesiana

AIM: to compare the anti-malarial effect among sambiloto extract, chloroquine and artemisinin-only as well as those of their combination. METHODS: the study was conducted in Central Biomedical Laboratory, Faculty of Medicine, Brawijaya University, Malang, Indonesia from January to February 2006. Malaria culture used Plasmodium falciparum of Papua strain (2300) that was obtained from Namru-2 Jakarta. Five drugs applied in this test; those were chloroquine, artemisinin, the extract of sambiloto, the combination of sambiloto and chloroquine, and the combination of sambiloto and artemisinin.

Author(s): 
Zein, Umar
Fitri, Loeki E.
Saragih, Awaluddin
Publication Title: 
Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica

OBJECTIVE: To isolate and elucidate the constituents from stem of Chirita longgangensis var. hongyao. METHOD: The constituents were extracted with methanol and isolated by chromatography on silica gel, Sephadex LH-20 and ODS. The structures were determined by NMR and MS spectral analysis.

Author(s): 
Wang, Man-Yuan
Yang, Lan
Tu, You-you
Publication Title: 
Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica

OBJECTIVE: To isolate and elucidate the constituents from stem of Chirita longgangensis var. hongyao. METHOD: The constituents were extracted with methanol and isolated by chromatography on silica gel, Sephadex LH-20 and ODS. The structures were determined by NMR and MS spectral analysis. RESULT: Seven compounds were identified as 2-hydroxy-7-methyl-9, 10-anthraquinone (1), 2-methyl-9, 10-anthraquinone (tectoquinone) (2), ursolic acid (3), vanillic acid (4), beta-sitosteryl-D-glucoside-6'-palmitate (5), beta-sitosterol (6), daucosterol (7), respectively.

Author(s): 
Wang, Man-Yuan
Yang, Lan
Tu, You-you
Publication Title: 
Acta Biochimica Polonica

Aromatic plant species present in the natural Park of Tuscany Archipelago are used as flavoring agents and spices, as dietary supplements and in cosmetics and aromatherapy. The plants are usually collected from wild stands, inducing a depletion of the natural habitat. Therefore, micropropagation of these aromatic plants can play a role in the protection of the natural ecosystem, can guarantee a massive sustainable production and can provide standardized plant materials for diverse economical purposes.

Author(s): 
Pistelli, Laura
Noccioli, Cecilia
D'Angiolillo, Francesca
Pistelli, Luisa
Publication Title: 
Bioscience, Biotechnology, and Biochemistry

Kothala himbutu is a traditional Ayurvedic medicinal plant used to treat diabetes. We aimed to evaluate the safety of an aqueous extract of Kothala himbutu stem (KTE) in normal mice. The mice were divided into two groups: one was administered KTE and the other distilled water for 3 weeks. During the test period, the groups showed no significant differences in body weight gain or plasma parameters, such as fasting blood glucose level, oral glucose tolerance test, or aspartate transaminase (AST) or alanine transaminase (ALT) activity.

Author(s): 
Im, Ryanghyok
Mano, Hiroshi
Nakatani, Sachie
Shimizu, Jun
Wada, Masahiro
Publication Title: 
Phytotherapy research: PTR

The effect of a standardized extract of Bacopa monniera Linn. was assessed on rat brain frontal cortical, striatal and hippocampal superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) activities, following administration for 7, 14 or 21 days. The effects induced by this extract (bacoside A content 82% +/- 0.5%), administered in doses of 5 and 10 mg/kg, orally, were compared with the effects induced by (-) deprenyl (2 mg/kg, p. o.) administered for the same time periods.

Author(s): 
Bhattacharya, S. K.
Bhattacharya, A.
Kumar, A.
Ghosal, S.
Publication Title: 
Fitoterapia

One of the most widely used herbs in Ayurvedic medicine is Ashwaghanda, Withania somnifera, a shrub commonly found on the Indian subcontinent. As this plant is increasingly becoming a popular adaptogenic in the western world, analytical methods for its identification and quality control are in demand. Thus, a HPLC method for the determination of withaferin A and withanolide D was developed. The system was successfully used to investigate the presence of the markers in different W. somnifera plant parts as well as to analyze their content in market products.

Author(s): 
Ganzera, M.
Choudhary, M. I.
Khan, I. A.

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