Sarcoma

Publication Title: 
Experimental Cell Research

Soft tissue sarcomas (STS) are characterized by co-participation of several epigenetic and genetic events during tumorigenesis. Having bypassed cellular senescence barriers during oncogenic transformation, the factors further affecting growth rate of STS cells remain poorly understood.

Author(s): 
Becerikli, Mustafa
Jacobsen, Frank
Rittig, Andrea
Kˆhne, Wiebke
Nambiar, Sandeep
Mirmohammadsadegh, Alireza
Stricker, Ingo
Tannapfel, Andrea
Wieczorek, Stefan
Epplen, Joerg Thomas
Tilkorn, Daniel
Steinstraesser, Lars
Publication Title: 
Journal of Clinical Pathology
Author(s): 
Hudson, G.
Blackburn, E. K.
Ghosh, M. L.
Publication Title: 
Cancer

BACKGROUND: Sarcomatoid features in renal cell carcinoma may represent an aggressive subclone arising from the primary tumor. The patterns of metastases for these tumors were evaluated to determine if sarcomatoid features were retained at metastasis and whether the percentage of sarcomatoid features in the primary tumor influenced spread. METHODS: All patients with sarcomatoid features found at nephrectomy with synchronous or metachronous resection of metastases were evaluated. The histology, grade, and percentage of sarcomatoid features in the primary and metastatic site were recorded.

Author(s): 
Shuch, Brian
Said, Jonathan
LaRochelle, Jeffrey C.
Zhou, Ying
Li, Gang
Klatte, Tobias
Pouliot, Frederic
Kabbinavar, Fairooz F.
Belldegrun, Arie S.
Pantuck, Allan J.
Publication Title: 
BMC complementary and alternative medicine

BACKGROUND: Crassocephalum crepidioides, a plant distributed in Okinawa Islands, is known in folk medicine; however, its anticancer activity has not been investigated. The aim of this study was to determine the in vitro and in vivo antitumor activities of C. crepidioides on murine Sarcoma 180 (S-180) and related molecular mechanisms. METHODS: The antitumor effect of C. crepidioides was evaluated in S-180-cell-bearing mice. Cell growth was assessed using a colorimetric assay. Nitrite and nitrate levels were measured by colorimetry.

Author(s): 
Tomimori, Koh
Nakama, Shinji
Kimura, Ryuichiro
Tamaki, Kazumi
Ishikawa, Chie
Mori, Naoki
Publication Title: 
The Journal of Bone and Joint Surgery. American Volume

BACKGROUND: Symptoms arising from primary bone sarcoma of the pelvic girdle are often insidious in onset and nonspecific in nature. To make the subtle initial signs and symptoms of these tumors more apparent to clinicians, we studied a cohort of patients who had a primary bone sarcoma of the pelvic girdle. Our purpose was to describe the initial clinical findings and to evaluate the duration, frequency, and implications of delays in the treatment of these tumors. METHODS: We retrospectively analyzed the data on sixty-eight patients who had a primary bone sarcoma of the pelvic girdle.

Author(s): 
Wurtz, L. D.
Peabody, T. D.
Simon, M. A.
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