Support Vector Machines

Publication Title: 
Journal of Neuroengineering and Rehabilitation

BACKGROUND: This study investigates measures of mindfulness meditation (MM) as a mental practice, in which a resting but alert state of mind is maintained. A population of older people with high stress level participated in this study, while electroencephalographic (EEG) and respiration signals were recorded during a MM intervention. The physiological signals during meditation and control conditions were analyzed with signal processing. METHODS: EEG and respiration data were collected and analyzed on 34 novice meditators after a 6-week meditation intervention.

Author(s): 
Ahani, Asieh
Wahbeh, Helané
Nezamfar, Hooman
Miller, Meghan
Erdogmus, Deniz
Oken, Barry
Publication Title: 
Journal of Neuroengineering and Rehabilitation

BACKGROUND: This study investigates measures of mindfulness meditation (MM) as a mental practice, in which a resting but alert state of mind is maintained. A population of older people with high stress level participated in this study, while electroencephalographic (EEG) and respiration signals were recorded during a MM intervention. The physiological signals during meditation and control conditions were analyzed with signal processing. METHODS: EEG and respiration data were collected and analyzed on 34 novice meditators after a 6-week meditation intervention.

Author(s): 
Ahani, Asieh
Wahbeh, Helané
Nezamfar, Hooman
Miller, Meghan
Erdogmus, Deniz
Oken, Barry
Publication Title: 
Zhong Xi Yi Jie He Xue Bao = Journal of Chinese Integrative Medicine

In this paper, factors contributing to the formation of pulse wave were analyzed based on hemodynamic principles. It is considered that formation of pulse wave was related to its propagation and reflection characteristics. Propagation of the pulse wave was characterized by pulse wave velocity, and reflection of the pulse wave was characterized by reflection coefficient.

Author(s): 
Guo, Rui
Wang, Yi-qing
Yan, Hai-Xia
Li, Fu-Feng
Yan, Jian-Jun
Xu, Zhao-Xia
Liu, Guo-Ping
Publication Title: 
PLoS computational biology

The H1N1 influenza pandemic of 2009 has claimed over 18,000 lives. During this pandemic, development of drug resistance further complicated efforts to control and treat the widespread illness. This research utilizes traditional Chinese medicine Database@Taiwan (TCM Database@Taiwan) to screen for compounds that simultaneously target H1 and N1 to overcome current difficulties with virus mutations. The top three candidates were de novo derivatives of xylopine and rosmaricine.

Author(s): 
Chang, Su-Sen
Huang, Hung-Jin
Chen, Calvin Yu-Chian
Publication Title: 
BMC complementary and alternative medicine

BACKGROUND: In Traditional Chinese Medicine (TCM), the lip diagnosis is an important diagnostic method which has a long history and is applied widely. The lip color of a person is considered as a symptom to reflect the physical conditions of organs in the body. However, the traditional diagnostic approach is mainly based on observation by doctor's nude eyes, which is non-quantitative and subjective. The non-quantitative approach largely depends on the doctor's experience and influences accurate the diagnosis and treatment in TCM.

Author(s): 
Li, Fufeng
Zhao, Changbo
Xia, Zheng
Wang, Yiqin
Zhou, Xiaobo
Li, Guo-zheng
Publication Title: 
PloS One

Pancreatic triacylglycerol lipase (PNLIP) are primary lipases that are critical for triacylglyceride digestion in human. Since reduced metabolism of triacylglyceride might be a plausible concept for weight loss, we screened for potential PNLIP inhibitors from traditional Chinese medicine (TCM) with the aim to identify weight loss candidate compounds.

Author(s): 
Chen, Kuan-Yu
Chang, Su-Sen
Chen, Calvin Yu-Chian
Publication Title: 
Scientific Reports

FAAH-like anandamide transporter (FLAT) regulates anandamide transport for hydrolysis and may be an attractive drug target for pain regulation. We aimed to discover potential FLAT antagonists from traditional Chinese medicine (TCM) using virtual screening, ligand-based drug design and molecular dynamics simulation (MD). Guineensine and Retrofractamide A exhibited high Dock Scores in FLAT.

Author(s): 
Tou, Weng Ieong
Chang, Su-Sen
Lee, Cheng-Chun
Chen, Calvin Yu-Chian
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