Publication Title: 
Journal of Diabetes Investigation

AIMS/INTRODUCTION: A meta-analysis was carried out to evaluate the efficacy of yoga in adults with type 2 diabetes mellitus. MATERIALS AND METHODS: The PubMed, EMBASE and Cochrane databases were searched to obtain eligible randomized controlled trials. The primary outcome was fasting blood glucose, and the secondary outcomes included glycosylated hemoglobin A1c, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglyceride and postprandial blood glucose. Weighted mean differences and 95% confidence intervals (CIs) were calculated.

Cui, Jie
Yan, Jun-Hong
Yan, Li-Ming
Pan, Lei
Le, Jia-Jin
Guo, Yong-Zhong
Publication Title: 
The Cochrane Database of Systematic Reviews

BACKGROUND: A sedentary lifestyle and stress are major risk factors for cardiovascular disease (CVD). Since yoga involves exercise and is thought to help in stress reduction it may be an effective strategy in the primary prevention of CVD. OBJECTIVES: To determine the effect of any type of yoga on the primary prevention of CVD.

Hartley, Louise
Dyakova, Mariana
Holmes, Jennifer
Clarke, Aileen
Lee, Myeong Soo
Ernst, Edzard
Rees, Karen
Publication Title: 
Wiener Medizinische Wochenschrift (1946)

Pumpan in a dosage of 3 x 10 drops daily over 6 weeks does not differ in its effect on systolic and diastolic blood pressure significantly from placebo. The tolerance was excellent: not one single patient had to be withdrawn from the study due to side effects. Blood lipids (cholesterol, HDL-, LDL-cholesterol and triglyzerides) did not change, neither in the placebo nor in the verum group.

Hitzenberger, Gerhart
Rehak, Peter H.
Publication Title: 
International Journal of Cardiology

The effect of orally administered indigenous drugs Terminalia arjuna, T. belerica and T. chebula were investigated on experimental atherosclerosis. Rabbits were fed a cholesterol-rich diet to induce atherosclerosis. The three drugs were fed along with cholesterol. At the end of the experimental period the animals were killed and their plasma and tissue lipid components estimated. Atherosclerotic lesions of the aorta were examined histologically. T. arjuna was found to be the most potent hypolipidemic agent and induced partial inhibition of rabbit atheroma. The results indicate that T.

Shaila, H. P.
Udupa, S. L.
Udupa, A. L.
Publication Title: 

Calorie restriction extends lifespan in organisms ranging from yeast to mammals. In yeast, the SIR2 gene mediates the life-extending effects of calorie restriction. Here we show that the mammalian SIR2 orthologue, Sirt1 (sirtuin 1), activates a critical component of calorie restriction in mammals; that is, fat mobilization in white adipocytes. Upon food withdrawal Sirt1 protein binds to and represses genes controlled by the fat regulator PPAR-gamma (peroxisome proliferator-activated receptor-gamma), including genes mediating fat storage.

Picard, FrÈdÈric
Kurtev, Martin
Chung, Namjin
Topark-Ngarm, Acharawan
Senawong, Thanaset
Machado De Oliveira, Rita
Leid, Mark
McBurney, Michael W.
Guarente, Leonard
Publication Title: 
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences

BACKGROUND: Families of centenarians have high levels of plasma high-density lipoprotein (HDL) cholesterol, which may have neurological as well as cardiovascular protective effects during aging. Because plasma HDL level declines progressively with aging, we examined whether centenarians with higher plasma HDL levels have better cognitive function.

Atzmon, Gil
Gabriely, Ilan
Greiner, William
Davidson, Deborah
Schechter, Clyde
Barzilai, Nir
Publication Title: 
Clinical Cardiology

BACKGROUND: Asian Indian women have a higher rate of coronary artery disease (CAD) than do other ethnic groups, despite similar conventional risk factors and lipid profiles. Smaller high-density lipoprotein cholesterol (HDL-C) particle size is associated with reduced cardiac protection or even an increased risk of CAD. Exceptional longevity correlates better with larger HDL-C particle sizes.

Bhalodkar, Narendra C.
Blum, Steve
Rana, Thakor
Kitchappa, Radha
Bhalodkar, Ami N.
Enas, Enas A.
Publication Title: 
Lipids in Health and Disease

BACKGROUND: The -493G/T polymorphism in the microsomal triglyceride transfer protein (MTP) gene is associated with lower serum low-density lipoprotein cholesterol (LDL-C) and triglyceride (TG) levels and longevity in several populations, but the results are inconsistent in different racial/ethnic groups. The current study was to investigate the plausible association of MTP -493G/T polymorphism with serum lipid levels and longevity in Zhuang long-lived families residing in Bama area, a famous home of longevity in Guangxi, China.

Pan, Shang-Ling
Luo, Xiao-Qiu
Lu, Ze-Ping
Lu, Shao-Hua
Luo, Huan
Liu, Cheng-Wu
Hu, Cai-You
Yang, Ming
Du, Li-Li
Song, Zhen
Pang, Guo-Fang
Wu, Hua-Yu
Huang, Jin-Bo
Peng, Jun-hua
Yin, Rui-Xing
Publication Title: 
PloS One

Borage (Borago officinalis L.) seed oil has been used as a treatment for various degenerative diseases. Many useful properties of this oil are attributed to its high gamma linolenic acid content (GLA, 18:3 ?-6). The purpose of this study was to demonstrate the safety and suitability of the use of borage seed oil, along with one of its active components, GLA, with respect to DNA integrity, and to establish possible in vivo toxic and in vitro cytotoxic effects.

Tasset-Cuevas, Inmaculada
Fern·ndez-Bedmar, Zahira
Lozano-Baena, MarÌa Dolores
Campos-S·nchez, Juan
de Haro-BailÛn, Antonio
MuÒoz-Serrano, AndrÈs
Alonso-Moraga, Angeles
Publication Title: 
Journal of the American Geriatrics Society
Berman, B. H.
Leon, D. F.


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