Vitamin B 12

Publication Title: 
Quintessence International (Berlin, Germany: 1985)

OBJECTIVE: Burning mouth syndrome (BMS) is a common chronic pain condition that lacks a satisfactory treatment approach. This systematic review was designed to examine the effects of acupuncture or acupoint injection on the management of BMS and to evaluate the evidence supporting the use of acupuncture therapy for BMS in clinical practice.

Author(s): 
Yan, Zhimin
Ding, Ning
Hua, Hong
Publication Title: 
Annals of Nutrition & Metabolism

BACKGROUND: A vegetarian diet is considered to promote health and longevity and reduce the risk of cardiovascular diseases and cancer. However, a vegetarian diet may be deficient in some nutrients. Exclusion of animal products in vegetarian diets may affect the status of certain B-vitamins, and further cause the rise of plasma homocysteine concentration. OBJECTIVE: The nutritional status of various B-vitamins (B(1), B(2), B(6), B(12), folic acid) and the concentration of homocysteine in blood plasma of omnivores (n = 40), vegetarians (n = 36) and vegans (n = 42) in Austria was evaluated.

Author(s): 
Majchrzak, D.
Singer, I.
M‰nner, M.
Rust, P.
Genser, D.
Wagner, K.-H.
Elmadfa, I.
Publication Title: 
British Medical Journal
Author(s): 
Blackburn, E. K.
Spray, G. H.
Swan, H. T.
Tudhope, G. R.
Wilson, G. M.
Publication Title: 
British Medical Journal
Author(s): 
Blackburn, E. K.
Cohen, H.
Wilson, G. M.
Publication Title: 
British Journal of Haematology
Author(s): 
Blackburn, E. K.
Swan, H. T.
Tudhope, G. R.
Wilson, G. M.
Publication Title: 
British Medical Journal
Author(s): 
Blackburn, E. K.
Burke, J.
Roseman, C.
Wayne, E. J.
Publication Title: 
Current Drug Abuse Reviews

Addiction research focusing on homocysteine metabolism and its association with aspects of alcohol dependence has revealed important findings. Recent literature on this topic has been taken into account for the review provided. Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the homocysteine metabolism. Plasma homocysteine levels are influenced by the single-nucleotide polymorphism (SNP) MTHFR C677T. Besides genetic factors, environmental factors have an impact on homocysteine plasma levels too.

Author(s): 
Lutz, Ulrich C.
Publication Title: 
The Journal of Maternal-Fetal & Neonatal Medicine: The Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

Preterm pregnancies account for approximately 10% of the total pregnancies and are associated with low birth weight (LBW) babies. Recent studies have shown that LBW babies are at an increased risk of developing brain disorders such as cognitive dysfunction and psychiatric disorders. Maternal nutrition, particularly, micronutrients involved in one-carbon metabolism (folic acid, vitamin B(12), and docosahexaenoic acid (DHA)) have a major role during pregnancy for developing fetus and are important determinants of epigenesis.

Author(s): 
Dhobale, Madhavi
Joshi, Sadhana
Publication Title: 
Current Opinion in Psychiatry

PURPOSE OF REVIEW: Nutrition exerts a pervasive impact on normal and pathological conditions of the nervous system. One critical pathway is the methionine cycle, in which folate and B12 convert homocysteine to methionine, which is in turn converted to S-adenosyl methionine (SAM; the major methyl donor). As a consequence of methylation, however, SAM is converted to the neurotoxin homocysteine and must be excreted or drawn back into the methionine cycle, which requires additional folate and B12.

Author(s): 
Shea, Thomas B.
Rogers, Eugene
Publication Title: 
Arteriosclerosis, Thrombosis, and Vascular Biology

OBJECTIVE: Hypercholesterolemia is a major risk factor for coronary artery disease. Therapeutic lifestyle changes include dietary modifications such as inclusion of phytosterols, which effectively lowers low-density lipoprotein (LDL) cholesterol in margarines and other fats. Their effectiveness in nonfat moieties is not yet established. The aim of this study was to examine if phytosterols alter the plasma lipoprotein profile when incorporated into nonfat orange juice.

Author(s): 
Devaraj, Sridevi
Jialal, Ishwarlal
Vega-López, Sonia

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